Baicalein links macrophage M2 polarization with reduced synovial inflammation to alleviate gouty arthritis.

Front Immunol · 2026 · PMC13149162 · PMID 42112357

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

0.0500

boldest claim

The sentences

highly significantP < 0.001actually significant

Following baicalein pretreatment, cell migration was markedly inhibited: the wound closure rate in the high-dose group decreased to 6.3%, showing a highly significant difference compared to the Model group (P < 0.001).

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did not reach statistical significanceP > 0.05actually significant

In contrast, the Low-dose group exhibited a marginal reduction to 2.91 ± 0.11 mm at t7, which did not reach statistical significance compared to the Model group ( P > 0.05 ) ( Table 2 ).

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showed a trendno p-value reported

The medium and low-dose groups also showed a trend of improvement, though the effects were less pronounced than in the high-dose group.

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