Barely Significant
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Safety and efficacy of percutaneous nephrolithotomy in elderly patients: a systematic review and meta-analysis by the EAU-YAU urolithiasis and EAU endourology sections.

World J Urol · 2026 · PMC13149612 · PMID 42089913

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a clear trendno p-value reported
Although larger tract sizes (standard PCNL) were predominantly used in the studies included in the present meta-analysis and are still widely employed in routine practice across many centres worldwide, contemporary PCNL practice shows a clear trend toward progressive miniaturization of the instrumentation and increasing use of smaller access sheaths.

also in 19,460 other papers

Our meta-analysis also demonstrated a trend toward an increased risk of post-procedural blood transfusions in elderly patients; however, this association did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.