Impact of concurrent autoimmune conditions on clinical outcomes and leukaemic transformation in chronic myelomonocytic leukaemia.

J Clin Pathol · 2026 · PMC13151462 · PMID 41781199

Europe PMC DOI

hedged sentences

0.0640

closest p · 1.3× alpha

0.0780

boldest claim

The sentences

did not reach statistical significancep=0.064so close (0.05 < p ≤ 0.1)

Leukaemic transformation occurred more frequently in patients without SIADs (31.6% vs 13.8%), although the difference did not reach statistical significance (p=0.064).

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showed a trendp=0.078so close (0.05 < p ≤ 0.1)

Patients with SIADs showed a trend toward lower frequencies of ASXL1 (p=0.078) and NRAS (p=0.080) mutations.

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