Barely Significant
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Subtype-specific prognostic impact of TNIK in medulloblastoma.

J Neurooncol · 2026 · PMC13156172 · PMID 42101697

2
hedged sentences
0.4600
closest p · 9.2× alpha
0.4600
boldest claim

The sentences

did not reach statistical significanceP = 0.46not close (p > 0.1)
When combining Group 3 and Group 4 tumors, strong TNIK expression was observed in 5/15 cases (33.3%); however, compared with SHH MBs, this did not reach statistical significance (Fisher’s exact test, P = 0.46) (Fig. 3 B).

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a strong trendno p-value reported
However, in Group 4 MBs, there was a strong trend suggesting that TNIK may serve as an independent prognostic marker in this subgroup (Fig. 2 D).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.