Impact of biologic class and treatment line on psoriatic arthritis risk in psoriasis: a population-based cohort study.

RMD Open · 2026 · PMC13157781 · PMID 42097693

Europe PMC DOI

hedged sentence

—

closest p

—

boldest claim

The sentences

did not reach statistical significancep=0.073so close (0.05 < p ≤ 0.1)

showed a trendno p-value reported

Therapies targeting IL-17 and IL-12/23 inhibitors also showed a trend toward reduced arthritis risk compared with TNF inhibitors, but these associations did not reach statistical significance (IL-17: HR 0.62; 95% CI 0.37 to 1.04; p=0.073; IL-12/23: HR 0.66; 95% CI 0.36 to 1.24; p=0.196).

also in 53,322 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.