Immune-inflammation index as prognostic markers in metastatic castration-resistant prostate cancer: a systematic review and meta-analysis.

Front Oncol · 2026 · PMC13158060 · PMID 42125686

Europe PMC DOI

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closest p

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boldest claim

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failed to reach statistical significancep=0.12not close (p > 0.1)

highly significantno p-value reported

The prognostic value of PLR was highly significant in European populations (HR = 1.66) but failed to reach statistical significance in Asian cohorts (HR = 1.28, p=0.12).

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did not reach statistical significanceno p-value reported

While some subgroups (such as American cohorts and combination therapy) did not reach statistical significance, these analyses were limited by small sample sizes.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.