Consolidation thoracic radiotherapy after chemoimmunotherapy provides survival benefit in elderly patients with extensive-stage small-cell lung cancer: a multicenter study.

Although hypofractionation showed a trend toward poorer outcomes compared with hyperfractionation (HR, 2.077; 95% CI, 0.788–5.478; p = 0.140), this difference did not reach statistical significance, likely due to the relatively small sample size in this group ( n = 17).

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In the subgroup of patients with liver metastasis, TRT was associated with a numerical improvement in median OS of approximately 4 months (HR, 0.71; 95% CI, 0.45–1.13), although this did not reach statistical significance.

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