Diagnostic value of gut microbiota profiling and circulating biomarkers to predict post-stroke infection in acute ischemic stroke.

Front Med (Lausanne) · 2025 · PMC13160763 · PMID 42130777

Europe PMC DOI

hedged sentences

0.3640

closest p · 7.3× alpha

0.3640

boldest claim

The sentences

did not reach statistical significancep = 0.364not close (p > 0.1)

The F/B ratio was higher in the non-infection group compared with the infection group (median ratio ~130 vs ~30, respectively), although the difference did not reach statistical significance ( p = 0.364).

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showed a trendno p-value reported

Although both ratios (F/B and F/P) showed a trend toward reduction in infection cases, reflecting dysbiosis and expansion of Proteobacteria, their ROC performance suggests they are not reliable standalone biomarkers for distinguishing infection from non-infection.

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