Comparative analysis of therapeutic strategies in atrial fibrillation patients with left atrial appendage thrombus despite optimal NOAC therapy.

Clin Res Cardiol · 2026 · PMC13161005 · PMID 40327061

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0.0600

closest p · 1.2× alpha

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boldest claim

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did not reach statistical significancep = 0.06so close (0.05 < p ≤ 0.1)

Switching to VKA was also assessed in the multivariate model, with a trend toward better thrombus resolution, though it did not reach statistical significance (OR = 4.02 [0.93–17.4], p = 0.06, Supplementary Fig. 1 ).

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showed a trendno p-value reported

Diabetes (OR = 0.43 [0.18–1.03], p = 0.59], and lower LVEF (OR = 1.04 [1.0–1.07], p = 0.054) showed a trend toward persisting LAA thrombosis (Table 2 ).

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