Real-world use of thrombopoietic agents in treatment-naïve children with severe aplastic anemia: a multicenter retrospective study.

Sci Rep · 2026 · PMC13161418 · PMID 42115659

Europe PMC DOI

hedged sentences

0.5670

closest p · 11.3× alpha

0.5670

boldest claim

The sentences

did not reach statistical significancep = 0.567not close (p > 0.1)

31.8%), but these differences did not reach statistical significance ( p = 0.567 and 0.074, respectively).

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a strong trendno p-value reported

The estimated 5-year overall survival was 74%; although there was a strong trend toward improved survival in the TPO-RA monotherapy group compared to the TPO-RA + CsA group, both before and after salvage therapy, this did not reach statistical significance ( p = 0.092 and 0.193, respectively).

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