Changing Patterns in Hospitalisations of Patients with Systemic Lupus Erythematosus over Three Decades at a Tertiary Referral Centre in Catalonia.

J Clin Med · 2026 · PMC13164423 · PMID 42123141

Europe PMC DOI

hedged sentences

0.0570

closest p · 1.1× alpha

0.0570

boldest claim

The sentences

showed a trendp = 0.057so close (0.05 < p ≤ 0.1)

In multivariate analysis, overlap syndromes (OR 1.85, CI 1.42–2.40; p < 0.001), arterial hypertension (OR 1.55, 95% CI 1.16–2.1; p = 0.003), SLE flare (OR 1.77, 95% CI 1.33–2.33; p < 0.001), and vascular events (OR 3.11, 95% CI 1.80–5.38; p < 0.001) remained independently associated with adverse outcomes, while antimalarial use showed a trend towards protection (OR 0.78, 95% CI 0.60–1.01; p = 0.057) ( Table 5 ).

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did not reach statistical significanceno p-value reported

Although antimalarial use did not reach statistical significance, its protective trend reinforces the need for universal prescription in eligible patients.

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