Peripapillary Vessel Density Mediates the Relationship Between Axial Length and Visual Field Damage in Glaucoma.

In the expanded cohort, relative mediator effects were similarly directionally consistent but did not reach statistical significance.

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While these relative mediator effects were attenuated compared to absolute values (reflecting shared variance removal and reduced power), their directional consistency and near-significant effects in the primary cohort suggest that the observed mediation is not purely a magnification artifact.

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