Effects of Sex, Estradiol, and Acute Stress on Spontaneous Recovery of a Conditioned Touchscreen Response in Rats.

Neurosci Insights · 2026 · PMC13167318 · PMID 42137242

Europe PMC DOI

hedged sentences

0.0510

closest p · 1.0× alpha

0.0580

boldest claim

The sentences

approached significanceP = .051so close (0.05 < p ≤ 0.1)

The Block × Treatment × Stress interaction approached significance, F (1, 26) = 4.18, P = .051, suggesting a trend toward differential spontaneous recovery depending on the combination of treatment and stress.

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did not reach statistical significanceP = .058so close (0.05 < p ≤ 0.1)

Although the 3-way interaction did not reach statistical significance ( P = .058), the pattern of means suggested a potential early block-dependent estradiol effect under no-stress conditions.

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