Barely Significant
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Immunotherapy retreatment with serplulimab vs. chemotherapy in extensive-stage advanced small cell lung cancer.

Oncol Lett · 2026 · PMC13177285 · PMID 42145910

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closest p · 1.0× alpha
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The sentences

did not reach statistical significanceP>0.05actually significant
For other subgroups, including patients aged >65 years, those with ECOG PS 0 or 1, and those with first-line radiotherapy, serplulimab showed an improved PFS, although these results did not reach statistical significance compared with the chemotherapy group (all P>0.05).

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showed a trendno p-value reported
In the remaining subgroups, serplulimab showed a trend of OS benefit, but the differences compared with the chemotherapy group were not statistically significant (all P>0.05).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.