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Independent Prognostic Significance of Perforation in Colorectal Cancer: Insights From a Propensity Score-Matched Cohort Study.

Ann Gastroenterol Surg · 2026 · PMC13178268 · PMID 42146837

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showed a trendno p-value reported
In contrast, for OS, perforation (HR: 2.38, 95% CI: 0.96–5.88, p = 0.06) and pT4 (HR: 2.11, 95% CI: 0.86–5.14, p = 0.1) did not reach statistical significance but showed a trend toward worse prognosis.

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