Hormonal staining patterns and clinical outcomes in acromegaly: a 15-year single-center study.

Pituitary · 2026 · PMC13183702 · PMID 42149337

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did not reach statistical significanceno p-value reported

In the multivariable model, optic chiasm compression was independently associated with postoperative remission (OR 0.212, 95% CI 0.049–0.910, p = 0.037), whereas T2-MRI hypointensity, cavernous sinus invasion, and preoperative GH level did not reach statistical significance.

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showed a trendno p-value reported

Notably, SSA response rates showed a trend toward being higher in patients with GH/PRL adenomas compared with GH-only tumors (68.2% vs. 42.9%).

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