Whole-genome sequencing reveals an East Asian-specific rare variant of INPP5J associated with Alzheimer's disease.

Transl Psychiatry · 2026 · PMC13183990 · PMID 41951582

Europe PMC DOI

hedged sentence

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closest p

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boldest claim

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did not reach statistical significanceno p-value reported

showed a trendno p-value reported

The p.K687T mutation significantly decreased phosphatase activity, while another mutation, p.R15W, showed a trend toward decreased phosphatase activity that did not reach statistical significance.

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