Although tissue damage appeared more pronounced in WTSuHx than in KOSuHx mice (0.13±0.22), this difference did not reach statistical significance (P=n.s.).
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Certain role of extra-domain A containing fibronectin in the development of pulmonary hypertension in the sugen/hypoxia mouse model.
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The sentences
SuHx-induced KO mice (2.14±0.19 mm) showed a trend towards smaller RV basal compared to WTSuHx (2.57±0.15 mm), but no significant structural changes were observed within the KO groups after PH induction (P=n.s.).