Correlation of cerebrospinal fluid IL-6 as a marker of disease activity in patients with longitudinally extensive transverse myelitis.

BMJ Neurol Open · 2026 · PMC13185011 · PMID 42164172

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.2500

boldest claim

The sentences

borderline significancep=0.06so close (0.05 < p ≤ 0.1)

CSF protein showed borderline significance (β=0.15, p=0.06), while ANA positivity, pleocytosis, age and gender were not independently associated after adjustment.

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did not reach statistical significancep=0.25not close (p > 0.1)

Although males showed higher IL-6 levels than females, the difference did not reach statistical significance (p=0.25) ( table 1 ).

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showed a trendno p-value reported

Age and gender do not have a significant effect on disease activity although male gender and older age showed a trend towards higher EDSS score but it was not statistically significant.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.