Acute effects of "exercise snacks" during prolonged sitting on hemodynamics and peripheral vascular function: a three-level meta-analysis.

Nutr Metab (Lond) · 2026 · PMC13185272 · PMID 41965833

Europe PMC DOI

hedged sentences

0.0520

closest p · 1.0× alpha

0.1300

boldest claim

The sentences

approaching significanceP = 0.052so close (0.05 < p ≤ 0.1)

Egger’s test was approaching significance in the two-level model (t(30) = 2.03, P = 0.052), whereas the multilevel Egger’s test was non-significant (t(30) = 1.14, P = 0.26; Figure S18).

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did not reach statistical significanceP = 0.13not close (p > 0.1)

The three-level random-effects model showed that the effect of sedentary breaks on MAP did not reach statistical significance compared with continuous sitting (MD = − 0.66 mm Hg [95% CI, − 1.53, 0.21]; 95% PI [− 1.53, 0.21]; P = 0.13).

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a slight trendno p-value reported

Publication Bias: The funnel plot showed a slight trend of asymmetry (Figure S18), suggesting potential small-study effects, but the overall extent was limited.

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