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Diminished Signal-to-Noise Ratio Disrupts Somatosensory Population Encoding and Drives Tactile Hyposensitivity in the Fmr1<sup>-/y</sup> Autism Model.

Adv Sci (Weinh) · 2026 · PMC13185836 · PMID 41983266

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a strong trendno p-value reported
Direct genotype comparisons of decoding accuracy during stimulus presentation revealed a significant reduction in the model's accuracy to predict detected trials (Figure 2d‐left ) and a strong trend toward increased errors for non‐detected trials in Fmr1 −/y ‐hyposensitive mice (Figure 2d‐right ).

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While BMS partially ameliorated these phenotypes, the effects did not reach statistical significance for these measures.

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