Exploring glucocorticoid dose-response patterns in VEXAS syndrome: a pilot retrospective study.

Rheumatol Int · 2026 · PMC13186862 · PMID 42154291

Europe PMC DOI

hedged sentences

0.1300

closest p · 2.6× alpha

0.1300

boldest claim

The sentences

did not reach statistical significancep = 0.13not close (p > 0.1)

10.5 ± 3.2 and 13.2 ± 5.6 mg/day), although this difference did not reach statistical significance (p = 0.13, ANOVA; Supplementary Data S3 ).

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showed a trendno p-value reported

When stratified by UBA1 variant, patients with the p.M41V mutation showed a trend toward higher mean daily GC requirements compared with p.M41L and p.M41T (21.1 ± 7.4 vs. 10.5 ± 3.2 and 13.2 ± 5.6 mg/day), although this difference did not reach statistical significance (p = 0.13, ANOVA; Supplementary Data S3 ).

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