Barely Significant
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Clinical predictors of enzyme immunoassay accuracy in Clostridioides difficile infection: the impact of immune status and infection predisposing factors.

BMC Infect Dis · 2026 · PMC13188291 · PMID 41942988

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Notably, third-generation cephalosporin (CRO3) usage remained elevated in the FN group (ac) but did not reach statistical significance compared to the P group (a).

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a clear trendno p-value reported
Our study substantiates this finding objectively, as the FN group not only had lower rates of hyperleukocytosis and fever but also demonstrated a clear trend towards lower disease severity as measured by the Zar CDI severity score.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.