Preliminary modeling of brain metastases in breast cancer: a neural network approach to risk factor analysis.

BMC Cancer · 2026 · PMC13188353 · PMID 41943024

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

0.1050

boldest claim

The sentences

highly significantP < 0.001actually significant

Age distribution showed that patients aged ≤ 40 were more frequently observed in the BBM group compared to those aged > 40, with a highly significant difference ( P < 0.001).

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near-significantP = 0.043actually significant

Specifically, the distribution across HER2/HR subgroups showed that HER2–HR + and HER2–HR– patterns were unevenly represented between BBM and non-BBM groups, with chi-square tests indicating significant or near-significant differences ( P = 0.043 and P = 0.085, respectively) (Table 1 ).

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did not reach statistical significanceP = 0.105not close (p > 0.1)

HER2 status alone did not reach statistical significance ( P = 0.105), but combined HER2 and HR categories revealed important differences.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.