Fat reduction mediates the efficacy of intensive lifestyle interventions on fertility-sparing treatment in overweight patients with endometrial cancer and intraepithelial neoplasia.

Acta Obstet Gynecol Scand · 2026 · PMC13191789 · PMID 42015911

Europe PMC DOI

hedged sentences

0.0660

closest p · 1.3× alpha

0.0660

boldest claim

The sentences

did not reach statistical significancep = 0.066so close (0.05 < p ≤ 0.1)

Although these differences did not reach statistical significance ( p = 0.066 and p = 0.184, respectively), a strong trend toward clinical benefit was observed.

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a strong trendp = 0.066so close (0.05 < p ≤ 0.1)

Among patients attempting natural pregnancy, the intervention group showed a strong trend toward a higher pregnancy rate (81.8% vs. 46.2%, p = 0.066).

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