However, given the high heterogeneity observed for some diversity indices, the pooled estimates should be regarded as indicative of an overall trend rather than a precise effect size.
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Machine learning-driven clinical decision support for liver cirrhosis: a gut microbiome-based web prediction model with explainable AI integration.
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In contrast, Lachnospira showed a clear trend of negative SHAP values, suggesting that elevated levels of this genus correlated with reduced model output (i.e., a push toward the “Low” feature value class).
Other indices (Observed, Chao1, Fisher, PD) exhibited downward trends but did not reach statistical significance (Figure S1).