Evaluating montelukast-second-generation antihistamine combinations versus monotherapy in allergic rhinitis: A network meta-analysis.

Asia Pac Allergy · 2026 · PMC13193261 · PMID 42182608

Europe PMC DOI

hedged sentences

0.0660

closest p · 1.3× alpha

0.0660

boldest claim

The sentences

approached significanceP = 0.066so close (0.05 < p ≤ 0.1)

Similarly, for NNSS in adults, results were nonsignificant, although the intervention sample size approached significance ( P = 0.066).

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a negative trendno p-value reported

Although no moderators reached significance, visual trends in Figure 4 D–F suggest possible positive associations with publication year and follow-up, and a negative trend with sample size.

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a possible trendno p-value reported

Rhinoconjunctivitis quality of life questionnaire (0–6) Based on the results of the NMA, the combination of montelukast with sgAHs showed a possible trend toward improved symptom control compared to montelukast monotherapy in adult patients with AR.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.