Immune profiling in trigeminal neuralgia reveals altered cytokine and chemokine signatures in cerebrospinal fluid and serum.

Front Pharmacol · 2026 · PMC13193973 · PMID 42181868

Europe PMC DOI

hedged sentences

—

closest p

—

boldest claim

The sentences

did not reach statistical significanceno p-value reported

Although these associations did not reach statistical significance, they may point to subtle systemic immune alterations accompanying TN.

also in 111,027 other papers

showed a trendno p-value reported

Descriptive analyses showed a trend toward higher circulating levels of M-CSF in patients with TN, whereas IL-1ra exhibited the opposite pattern ( Supplementary Table S2 ).

also in 53,322 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.