Carp collagen membrane for guided bone regeneration: evaluation in a rat femoral defect model.

Biomater Biosyst · 2026 · PMC13197808 · PMID 42181027

Europe PMC DOI

hedged sentences

0.0850

closest p · 1.7× alpha

0.1200

boldest claim

The sentences

borderline non-significantp = 0.085so close (0.05 < p ≤ 0.1)

Post-hoc analysis at 4 weeks demonstrated a significant difference between defects treated with the carp collagen membrane alone and those treated with Bio-Oss® + carp collagen membrane (p = 0.011), and a borderline non-significant difference between the carp collagen membrane alone and the Bio-Oss® + Bio-Gide® group (p = 0.085).

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did not reach statistical significancep = 0.12not close (p > 0.1)

Although median scores continued to rise from 12 to 16 weeks (17.0 → 24.5 → 25.0), the difference between 4 and 16 weeks did not reach statistical significance (p = 0.12), likely due to inter-subject variability.

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