Barely Significant
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A clinical and echocardiographic model to identify LVOT-related overestimation of aortic stenosis severity in transcatheter aortic valve replacement candidates.

Eur Heart J Imaging Methods Pract · 2026 · PMC13198208 · PMID 42182090

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showed a trendno p-value reported
9 , 23 , 24 In our study, patients who were reclassified to moderate AS based on hybrid AVA calculation (hybrid AVA >1.2 cm 2 ) showed a trend towards worse prognosis compared to those with true severe AS (hybrid AVA < 1 cm 2 ) or those with indeterminate AS (hybrid AVA 1.0–1.2 cm 2 ).

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a clear trendno p-value reported
According to LVOT area measurements, the mean difference was −162 mm 2 ± 98.2 mm 2 (limits of agreement: −354.5 to 30.5 mm 2 ) between echocardiography and CT, with a clear trend indicating that the absolute error between the two modalities increased with larger LVOT diameters ( Figure 2 A ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.