Barely Significant
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Clinical benefit of tenecteplase despite failed recanalization in late-window ischemic stroke: a post hoc analysis of the TRACE-3 trial.

BMC Med · 2026 · PMC13202816 · PMID 41992212

Europe PMCDOI
2
hedged sentences
0.1420
closest p · 2.8× alpha
0.1420
boldest claim

The sentences

did not reach statistical significanceP = 0.142not close (p > 0.1)
21.8%), though this did not reach statistical significance (adjusted RR 1.35, 95% CI 0.90–2.02, P = 0.142).

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showed a trendno p-value reported
In our analysis, patients with good collateral circulation showed a trend toward greater benefit from tenecteplase, but the interaction was not statistically significant ( P = 0.35).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.