Association of Iba1-Positive Macrophages and B7-H3-Positive Tumor Cells with Tumor Growth Kinetics in WHO Grade II Meningioma: A Pilot Watch-and-Wait Cohort Study.

Cancers (Basel) · 2026 · PMC13204069 · PMID 42192905

Europe PMC DOI

hedged sentences

0.0428

closest p · 0.9× alpha

0.0428

boldest claim

The sentences

nominally significantp = 0.0428actually significant

Individual immune components did not show significant linear correlations with RGR; on median-split stratification, high B7-H3-positive tumor cell density was associated with a nominally significant difference in RGR ( p = 0.0428, unadjusted).

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did not reach statistical significanceno p-value reported

Although these correlations did not reach statistical significance, likely due to the limited sample size ( n = 15), the effect sizes ( R ≈ 0.35) suggest a potential biological link between the immune microenvironment and tumor growth kinetics.

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