Barely Significant
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Gender Differences in Circulating TFAM Levels Are Associated with Functional Impairment and Sarcopenia.

Biomedicines · 2026 · PMC13204914 · PMID 42193471

Europe PMCDOI
3
hedged sentences
0.0700
closest p · 1.4× alpha
0.0700
boldest claim

The sentences

showed a trendp = 0.07so close (0.05 < p ≤ 0.1)
When stratified by sex, this study showed a trend toward higher sarcopenia prevalence in women with elevated TFAM levels, albeit this did not reach statistical significance ( p = 0.07).

also in 53,322 other papers

did not reach statistical significanceno p-value reported
Although the effect sizes were consistent with the overall association, these results did not reach statistical significance in sex-specific analyses, potentially reflecting reduced statistical power in the stratified subgroups.

also in 111,027 other papers

a positive trendno p-value reported
In men, those in the higher TFAM quartiles exhibited a greater prevalence of sarcopenia compared to the lowest quartile, though this association was not statistically significant despite a positive trend (OR = 2.02).

also in 11,005 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.