Baseline characteristics were generally comparable; however, HER2-positive patients showed a trend toward higher-grade tumors and were significantly less likely to receive anti-EGFR therapy.
← all excerpts
Prognostic and Treatment-Specific Predictive Implications of HER2 Expression in RAS Wild-Type Metastatic Colorectal Cancer: A Multicenter Retrospective Real-World Study.
3
—
—
The sentences
In our cohort, a numerical trend toward higher-grade tumors was observed in HER2-positive patients; however, this difference did not reach statistical significance.
In our cohort, a numerical trend toward higher-grade tumors was observed in HER2-positive patients; however, this difference did not reach statistical significance. Moreover, correlation analyses did not demonstrate a significant association between HER2 status and conventional histopathological features associated with tumor aggressiveness, including tumor grade, lymphovascular invasion, perineural invasion, and histological subtype.