Exploring the Utility of Cell-Free DNA Hydroxymethylation Profiling in Small-Cell Lung Cancer.

Int J Mol Sci · 2026 · PMC13207598 · PMID 42196386

Europe PMC DOI

hedged sentences

0.0900

closest p · 1.8× alpha

0.0900

boldest claim

The sentences

trending towards significancep = 0.09so close (0.05 < p ≤ 0.1)

Multivariable Cox regression revealed that stage was a significant factor ( p = 4.21 × 10 −6 ), while 5hmC was trending towards significance ( p = 0.09; Figure 2 F).

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approached significanceno p-value reported

Although stage remained the predominant predictor in Cox regression analysis, 5hmC approached significance, suggesting it may provide complementary prognostic value.

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