Anti-Inflammatory Properties of Curcumin as Add-On Therapy in Patients with MS-Prospective, Comparative, Randomized, Pilot Study.

Pharmaceutics · 2026 · PMC13210320 · PMID 42198213

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a decreasing trendno p-value reported

A decreasing trend in MRI lesion activity and reductions in specific microbiota-related markers, including the Eggerthella lenta -associated marker (i16a), were also observed.

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did not reach statistical significanceno p-value reported

During the subsequent 6-month follow-up period off treatment, relapse rates demonstrated a declining trend in both groups; however, this trend did not reach statistical significance.

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an increasing trendno p-value reported

In our study, the proportion of patients with CUA lesions in the IFN-CUR group exhibited a decreasing trend at month 6, whereas an increasing trend was observed in the comparison group.

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showed a trendno p-value reported

While IL-6 levels remained unchanged with curcumin, the untreated group showed a trend toward increased IL-6.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.