Dynamic changes in peripheral blood lymphocyte subsets predict the efficacy and prognosis of immune checkpoint inhibitors in metastatic osteosarcoma.

Front Immunol · 2026 · PMC13212053 · PMID 42212138

Europe PMC DOI

hedged sentences

—

closest p

—

boldest claim

The sentences

did not reach statistical significanceno p-value reported

Furthermore, while we observed numerical trends in several other lymphocyte subsets, these did not reach statistical significance.

also in 111,027 other papers

showed a trendno p-value reported

on nivolumab combined with sunitinib showed a trend toward superiority over monotherapy in certain subtypes, yet the overall ORR remained far below that observed in common solid tumors ( 10 , 14 ).

also in 53,322 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.