Sperm Imprinted Gene Methylation and DNA Fragmentation in ICSI Outcomes: A Pilot Study.

Epigenomes · 2026 · PMC13214655 · PMID 42201148

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a positive trendno p-value reported

Additionally, a positive trend between CpG3 and fertilisation rate was observed ( Table 7 ). 2.5.

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did not reach statistical significanceno p-value reported

Higher total H19 methylation levels were observed in the viable embryo (VE) group compared to the others, although this difference did not reach statistical significance.

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a negative trendno p-value reported

Total IGF2 methylation showed a positive correlation trend with sperm vitality ( Rho = 0.404, p = 0.078) and a negative trend with SDF (%) ( Table 7 ).

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