Dysregulation of astrocytic DNAJC6 contributes to sporadic Parkinson's disease pathogenesis.

J Clin Invest · 2026 · PMC13221221 · PMID 41955024

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did not reach statistical significanceno p-value reported

Combined overexpression in both neurons and astrocytes showed a trend toward greater reduction of α-syn aggregation than single–cell type targeting, although this did not reach statistical significance ( Supplemental Figure 17 ).

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showed a trendno p-value reported

HSP70 family members (HSPA6, HSPA1A, HSPA1B, and HSPA1L) and small heat shock proteins (HSPB1, HSPB2, and HSPB9) showed a trend toward upregulation ( Supplemental Figure 2B ).

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