sncRNA levels predict SNORD105B is a novel biomarker of chronic kidney disease risk and SGLT2 inhibitor response in type 2 diabetes.

Mol Ther Nucleic Acids · 2026 · PMC13223920 · PMID 42233107

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did not reach statistical significanceno p-value reported

Effect sizes were generally similar across groups, although most associations did not reach statistical significance ( Tables S9–S11 ; Figure S4 ).

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nominally significantno p-value reported

For the SGLT2 treatment analysis, most of the 34 nominally significant sncRNA associations did not remain statistically significant in the per-treatment regimen analysis, likely due to the small sample sizes within each subgroup, despite generally similar effect sizes across regimens.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.