Early predictors and outcomes of mechanical circulatory support use during single lung transplant for secondary pulmonary hypertension: A large single-center experience.

After adjustment, higher preoperative PVR (adjusted OR 1.25 per 1 WU increase, 95% CI 1.03–1.52, p = 0.024), higher LAS (adjusted OR 1.06 per 1-point increase, 95% CI 1.04–1.08, p < 0.0001), and higher intraoperative mPAP (adjusted OR 1.1 per 1 mmHg increase, 95% CI 1.05–1.16, p < 0.0001) remained independently associated with intraoperative MCS use, while right-sided transplant showed a trend toward independent association (adjusted OR 2.26, 95% CI 0.996–5.107, p = 0.051).

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There was no significant difference in pre-transplant TAPSE between MCS-assisted and no-MCS assisted patients (TAPSE 19.1 mm vs 18.2 mm, p=0.18) although when TAPSE was dichotomized into reduced (≤16 mm) or normal (≥17 mm), a reduced TAPSE was found to be associated with an increased use of intraoperative MCS use, however, this did not reach statistical significance (20.9% vs 12.6%, p=0.068).

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