A multi-stage validation of the C-reactive protein-triglyceride-glucose index for predicting mild cognitive impairment: evidence from clinical and nationwide prospective cohorts.

Front Endocrinol (Lausanne) · 2026 · PMC13225990 · PMID 42238234

Europe PMC DOI

hedged sentences

0.1350

closest p · 2.7× alpha

0.1350

boldest claim

The sentences

did not reach statistical significanceP = 0.135not close (p > 0.1)

The AUC for Model 2 (0.7066; 95% CI: 0.681–0.732) was numerically higher than that of Model 1 (0.7045; 95% CI: 0.679–0.730), although the difference did not reach statistical significance (P = 0.135).

also in 111,027 other papers

a significant trendno p-value reported

A significant trend was seen in Models 1 (P trend = 0.005) and Model 2 (P trend = 0.041) when CTI was examined as a categorical variable.

also in 9,775 other papers

highly significantno p-value reported

The trend across quartiles was highly significant, reinforcing the evidence that elevated CTI levels at baseline are a strong long-term predictor for the onset of cognitive impairment in the general population.

also in 132,142 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.