In contrast, the >60 years group showed a trend toward higher risk (unadjusted HR = 1.032, 95% CI 1.012–1.053, P = 0.001), which lost statistical significance after adjustment (adjusted HR = 1.015, 95% CI 0.994–1.037, P = 0.151).
Clinical subgroup analysis of BMI and risk of recurrent myocardial infarction Age and Gender Stratification: As shown in Table 4 , in patients aged ≤60 years, BMI was associated with a borderline significant protective effect against recurrent myocardial infarction in males (HR = 0.969, 95% CI 0.939–1.000, P = 0.052), while in females, this effect was not statistically significant (HR = 0.954, 95% CI 0.878–1.037, P = 0.268).
In contrast, in patients aged >60 years, an increase in BMI tends to be associated with an increased risk of recurrent myocardial infarction, although this association did not reach statistical significance after multivariable adjustment (Graphical abstract).