Hepatic arterial infusion chemotherapy plus tyrosine kinase inhibitors with or without PD-1 inhibitors for advanced hepatocellular carcinoma with VP4 portal vein tumor thrombosis: a retrospective cohort study.

Front Immunol · 2026 · PMC13229895 · PMID 42245629

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did not reach statistical significanceno p-value reported

Although these differences did not reach statistical significance due to limited sample size, the SMDs suggested potential confounding.

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showed a trendno p-value reported

In this subset, triple therapy showed a trend toward longer PFS than dual therapy, though the difference did not reach statistical significance (HR 0.70, 95% CI 0.39–1.26, P = 0.235).

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