Notably, the Fatty Acid score for Fibroblasts in NPC was higher than in CIH, but did not reach statistical significance (p < 0.05) ( Figures 2C, E, F f3, f5, 2G g3, g7).
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Exploring glycerophospholipid metabolism in nasopharyngeal carcinoma: interactions between malignant epithelial cells and CCL11-expressing fibroblasts.
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In the multivariate Cox regression analysis, the five-gene signature (riskScore) showed a trend toward worse prognosis (HR = 1.374, 95% CI: 0.916-2.061), though it did not reach statistical significance (P = 0.125), potentially due to limited sample size ( Supplementary Figure S3B ).