Baseline vitamin D status and clinical outcomes in advanced non-small cell lung cancer patients treated with nivolumab.

Sci Rep · 2026 · PMC13234407 · PMID 41981174

Europe PMC DOI

hedged sentences

0.0200

closest p · 0.4× alpha

0.0800

boldest claim

The sentences

narrowly missed significancep = 0.02actually significant

Moderate deficiency (10–20) showed a strong trend toward worse OS that narrowly missed significance. Liver metastasis was independently associated with significantly worse OS (adjusted HR 1.42, 95% CI 1.06–1.91, p = 0.02), consistent with published literature where HRs for liver metastasis typically range from 1.4 to 2.0.

also in 41 other papers

of borderline significancep = 0.07so close (0.05 < p ≤ 0.1)

Patients with 10–20 ng/mL also had poorer OS than ≥ 20 ng/mL (HR 1.31), although this difference was of borderline significance ( p = 0.07).

also in 482 other papers

did not reach statistical significancep = 0.08so close (0.05 < p ≤ 0.1)

Although these differences in ORR did not reach statistical significance (Chi-square p = 0.08, likely due to limited power), a numerical trend is evident.

also in 57,071 other papers

a numerical trendno p-value reported

Although these differences in ORR did not reach statistical significance (Chi-square p = 0.08, likely due to limited power), a numerical trend is evident.

also in 586 other papers

a strong trendno p-value reported

Moderate deficiency (10–20) showed a strong trend toward worse OS that narrowly missed significance.

also in 1,799 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.