HIV-1 Tat-induced VAPB disruption initiates a cascade of organellar failures culminating in neuronal lipid accumulation.

J Lipid Res · 2026 · PMC13234481 · PMID 42092489

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did not reach statistical significanceP > 0.05actually significant

showed a trendno p-value reported

Guanosine showed a trend toward decrease, and glucose-6-phosphate showed a trend toward increase, consistent with metabolic mismatch, though these did not reach statistical significance due to high biological variability in baseline nucleotide and glycolytic pools ( P > 0.05, Fig. 5 ).

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