Telomere length and clonal hematopoiesis interact to influence outcomes in hematopoietic stem cell transplantation.

Blood Adv · 2026 · PMC13235491 · PMID 41860374

Europe PMC DOI

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0.0640

closest p · 1.3× alpha

0.0640

boldest claim

The sentences

did not reach statistical significanceP = .064so close (0.05 < p ≤ 0.1)

A Cox proportional hazards model revealed that after adjusting for age, sex, and disease status before transplantation, above-median rLTL in patients without CH was associated with a 26% improvement in PFS (HR, 0.74; 95% CI, 0.56-0.98; P = .035), whereas the corresponding effect on OS did not reach statistical significance (HR, 0.71; 95% CI, 0.49-1.02; P = .064; Figure 1 F-G).

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difference was apparentno p-value reported

This difference was apparent when tracing RDW values for up to 20 days after ASCT, and withstood adjustment for renal function and the number of transfused red cell units.

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