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Restoring Septohippocampal Cholinergic Signaling Rescues Surgery-Induced Neurogenesis and Memory Deficits in Aged Mice.

Aging Cell · 2026 · PMC13238679 · PMID 42244222

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Four weeks after surgery, chronic activation significantly increased the number of newborn neurons in surgery mice, whereas the increase in control mice did not reach statistical significance; MEC co‐administration prevented this increase (Figure 6G,H ).

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showed a trendno p-value reported
Galantamine did not affect center time in control mice but showed a trend toward improvement in surgery mice (Figure 4D ).

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