Mapping the neurovascular landscape in aging and dementia: cerebral small vessel disease markers in a multicenter Latin American cohort.

Alzheimers Dement · 2026 · PMC13239890 · PMID 42192214

Europe PMC DOI

hedged sentences

0.0916

closest p · 1.8× alpha

0.0916

boldest claim

The sentences

did not reach statistical significancep = 0.0916so close (0.05 < p ≤ 0.1)

Although lacunes and microbleeds co‐occurred in only a minority of participants, lacunes were more prevalent among individuals with microbleeds (15.5%) than among those without microbleeds (8.4%), suggesting partial clustering of CSVD markers; however, this difference did not reach statistical significance ( p = 0.0916).

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showed a trendno p-value reported

In contrast, microbleed–WMH and lacune‐microbleed associations showed a trend only in AD.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.